Exploring the pleiotropic effects of - AVHANDLINGAR.SE
We've been told for years that 1 jan. 2021 — including immunomodulatory activity, protection against respiratory tract infections and pleiotropic effects on the cardiovascular system. Pleiotropic effects accompanying atrazine resistance were investigated in atrazine-resistant (AR) and susceptible (S) biotypes of horseweed (Conyza No pleiotropic effects on stem height or diameter growth were observed. The results establish a central role for the FRK2 activity in carbon flux to wood cellulose.
The pleiotropic effects attributed to statins are many. 1,2 They include increases in endothelial nitric oxide formation; flow-mediated vascular dilatation; suppression of vascular inflammation; reduction of circulating biomarkers that indicate inflammation (such as C-reactive protein); a reduction in T-cell activation with a decrease in cytokines; promotion of neovascularization in ischemic tissue; and … Statins may exert cardiovascular protective effects that are independent of LDL-cholesterol lowering called pleiotropic effects. 2018-12-14 MCP also reduces fibrosis to the kidney, liver, and adipose tissue. Other benefits of MCP include detoxification and improved immune function. This review summarizes the pleiotropic effects of MCP. Keywords: cancer; cardiovascular; fibrosis; galectin; inflammation; pectasol.
: producing more than one effect especially : having multiple phenotypic expressions a pleiotropic gene. Pleiotropic effects mediated by inhibition of isoprenoids correlate with the inhibition of cholesterol biosynthesis and are difficult to quantitate.
Immune cells lacking Y chromosome show dysregulation of
2005 Aug;8(2):89-91. Cancer Cell. 2005 Aug;8(2):93-5. Statins and the HMGCoA reductase pathway, beyond cholesterol.
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Pleiotropic effects of statins. However, the overall clinical benefits observed with statin therapy appear to be greater than what might be expected from changes in lipid profile alone, suggesting that the beneficial effects of statins may extend beyond their effects on serum cholesterol levels. Clusters of QTL for plant source capacity and seed traits may correspond to genes of metabolism having pleiotropic effects on source-sink relationships. When expressed during seed set, these genes may control the seed number and the NcotCel. When expressed during seed growth, they may control seed weight or seed protein content.
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than pleiotropic effects of statins for endothelial function in patients with dysglycaemia and coronary artery disease. Europ Heart J 2008; 29:1753-1760. 12. av PM NILSSON — Simvastatin versus ezetimibe: pleiotropic and lipid- lowering effects on endothelial function in humans. Circulation.
The term is often used to refer to a single gene defect that is expressed as
2019-09-24 · Although effects are pleiotropic and affect many cell cycle regulators, the main Cyclin-CDK complexes driving progression through G2 phase show differential regulation in CHH cells.
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Cholesterol Cholesterol is an essential component of cell membranes and is the immediate precursor of steroid hormones and bile acids. The rate-limiting enzyme in cholesterol biosynthesis in the liver is HMG-CoA reductase. 2014-04-08 · 3.
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2021-01-28 the production by a single gene of multiple phenotypic effects. The term is often used to refer to a single gene defect that is expressed as problems in multiple systems of the body, such as in osteogenesis imperfecta, where the gene causes defects in several different systems that contain collagen. 2014-04-08 Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity. Moeller BJ(1), Dreher MR, Rabbani ZN, Schroeder T, Cao Y, Li CY, Dewhirst MW. Author information: (1)Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA. 2020-06-06 PLEIOTROPIC EFFECTS OF STATINS Dr.RENJU.S.RAVI MD 2. Cholesterol Cholesterol is an essential component of cell membranes and is the immediate precursor of steroid hormones and bile acids. The rate-limiting enzyme in cholesterol biosynthesis in the liver is HMG-CoA reductase.